Specification
|
Concerning Product: |
| Article number | 153184XEP |
| Trade name / designation / denomination | Rutin, EP |
| CAS number | 153-18-4 |
| Other names / synonyms | •2,3-dihydro-4H-chromen-4-one;
•2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-oxanyl]oxymethyl]-2-oxanyl]oxy]-1-benzopyran-4-one;
•4-CHROMANONE;
•4-Chromanone;
•4-Chromanone [491-37-2];
•CHROMANONE;
•Chroman-4-one;
•Rutin hydrate;
•Rutin trihydrate;
•chroman-4-one; |
| EC number | 205-814-1 |
| Customs tariff number / CN code / TARIC | 29381000 |
| Molecular weight [g / mol] | 610.5175 |
| Formula | C27H30O16 |
| Parameter |
Test Method |
Specification |
Unit |
Organoleptic test |
| Appearance |
visual |
yellow or greenish-yellow crystalline powder |
Physical parameter |
| Substances insoluble |
|
in Menthol: ≤ 3,0 |
% |
| Loss on drying |
|
7,5 – 9,5 |
% |
| Solubility |
|
in Methanol: soluble |
| Solubility |
|
in Methylene Chloride: practically insoluble |
| Solubility |
|
in Water: practically insoluble |
| Solubility |
|
It dissolves in solution of Alkali Hydroxide. |
Identity |
| Assay |
Titration with 0.1 M N(C4H9)4OH |
95,0 – 101,0 |
% |
| Identification |
Dissolve 10 mg in 5 ml of alcohol R, add 1 g of Zn R and Hcl R1 |
a red color develops |
| Identification |
|
TLC: Principle spot is similar to that of reference solution |
| Infrared absorbtion spectrometry |
|
Conforms to the Rutin CRS spectrum. |
| UV spectroscopy |
UV/Vis absorption of menthol solution between 210 nm and 450nm |
Absorption maxima at 257 nm and 358 nm. Specific absorbance at 358 is 305-330 (anhydrous substance) |
Impurities |
| Sulphated ash |
|
≤ 0,1 |
% |
| Impurity |
|
A: Isoquercitroside ≤ 2,0 |
% |
| Impurity |
|
B: Kaempferol-3-rutinoside ≤ 2,0 |
% |
| Impurity |
|
C: Quercetin ≤ 2,0 |
% |
| Impurity |
at wavelength between 450 and 800 |
Light absorbing impurities: ≤ 0,10 |
| Impurity |
|
total: ≤ 4,0 |
% |
Residual Solvents |
| Residual solvents |
|
≤ 3000 |
ppm |
Microbiological data |
| Aerobic microorganisms |
|
≤ 1000 |
CFU/g |
| Escherichia Coli. |
|
Neg. |
|
| Yeast and Mould |
|
≤ 1000 |
CFU/g |
Supplemental information:
Shelf life:
3 years
Complies with monographie:
Ph.Eur. 9.0
Regional origin:
CN
Chemische Werke Hommel GmbH & Co.KG
This document was generated electronically and is valid without signature.
|
Waltrop, 09. Jun. 2021
|
We only confirm that we took over the data from our supplier accordingly. Despite careful working, errors in the
takeover are not totally excluded. Some or all parts off the document may be translated due to our best knowledge from the original
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